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Get comfortable again with Anusol Plus Suppositories for mess-free relief from itching and burning with an added anesthetic for extra pain relief from hemorrhoids. Designed with comfort in mind, Anusol contains a gentle astringent to reduce swelling, giving your hemorrhoids a better chance to heal. Anusol is the #1 pain-relief brand recommended by doctors and pharmacists for internal and external hemorrhoids. Its fast and effective formula relieves pain, so you can get moving again.